Immuno-oncology and virology

Dr. Sucheta De

How signal transduction networks steer the fate of cancer cells during oncolytic virus infection

  • Oncolytic viruses
  • Immuno-oncology
  • Signal transduction
  • Cell fate

Ph.D. in Immuno-oncology and Virology focused on how signal transduction networks steer the fate of cancer cells during oncolytic virus infection. My work integrates virology, cell biology, and therapeutic context to map the molecular decisions that enable viral oncolysis, stress responses, and anti-tumor effects. I aim to translate these mechanistic insights into strategies that improve oncolytic virotherapy and immuno-oncology outcomes.

Download CV
Portrait of Dr. Sucheta De
Fig. 1
Current focus
Oncolytic virus–cancer interactions
Nationality
India
01

Education

02

Research experience

Oct 2019 – Apr 2026

Research Scholar

Tel Aviv University·Tel Aviv, Israel

  • Supervisor: Prof. Marcelo Ehrlich
  • Thesis title: Signal transduction crossroads as fate determinants of the interactions of oncolytic viruses and cancer cells

Jan 2017 – Jul 2019

Master Student, Cellular and Molecular Virology Lab

Translational Health Science and Technology Institute·Faridabad, India

  • Supervisor: Dr. Guruprasad Medigeshi
  • Master’s Dissertation: Cloning and purification of Respiratory Syncytial Virus NS1 protein to identify interacting proteins
03

Selected publications

04

Skills

Immunology and virology

  • Flow cytometry, immunocytochemistry
  • Virus propagation and infection
  • Plaque and neutralization assays
  • Handling patient serum samples for immunological assays
  • BSL-2 handling of viruses
    • EHDV-TAU, VSV-DM51, HSV-1, JEV
    • Additional: Dengue (DenV1–4), RSV, rotavirus, WNV

Molecular biology

  • Western blotting, RT-PCR, cloning, transfection
  • Agarose gel electrophoresis, SDS-PAGE

Cell culture and in vivo models

  • Mammalian cell maintenance
  • Cell-based assays
  • Tumour and oncolytic virotherapy models (syngeneic melanoma, prostate cancer xenografts)

Imaging and analysis

  • Epifluorescence and confocal microscopy
  • Data organisation and statistical analysis
  • Basic bioinformatics

Scientific communication

  • Scientific writing, presentation, and documentation
05

Academic engagements

9–11 Oct 2024

30th European Cell Death Organisation Conference

Poster·Belval, Luxembourg

20 May 2024

2nd Retreat of Shmunis School of Biomedicine and Cancer Research

Flash talk and poster·Tel Aviv-Yafo, Israel

28 Jul 2022

1st Retreat of Shmunis School of Biomedicine and Cancer Research

Poster·Tel Aviv-Yafo, Israel

06

Grants and funding

2024

Shmunis Travel Grant and Tel Aviv University Travel Grant

Conference travel support

2019–2024

S Daniel Abraham Institute for Molecular Virology

Tel Aviv University funding for doctoral education

2022–2023

Shmunis Excellence Scholarship

Awarded in 2022 and 2023

2019

TATA Trust–Tel Aviv University PhD Scholarship

Funding for doctoral education following a competitive open call

07

Trainings and certifications

01 Mar 2020

Trained and certified for BSL2+ containment